Our experience with antidepressant treatment in the obese and type 2 diabetics.

نویسنده

  • S Svacina
چکیده

We established depressive symptoms prevalence in 100 patients recommended to our obesity clinic and we started antidepressant treatment in 41 of them. It has been noted that administration of SSRI leads to weight reduction after 6 months, but is followed by a weight increase later. Our experience shows that 12 months long administration of bupropion and tianeptine leads to continuous weight loss. Antidepressant administration leads to an increase in pharmacotherapy adherence, which is significantly higher than in diet and psychotherapy alone. In diabetics, antidepressants reduce glucose levels, too. Their influence on weight and diabetes compensation is, however, smaller than in "classic" anti-obesity drugs, sibutramine and orlistat.

برای دانلود رایگان متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

ارتباط سطح سرمی رزیستین با شاخص های مقاومت به انسولین در افراد چاق دیابتی و غیر دیابتی

Background: Resistin, an adipocyte secreted factor, has been suggested to link obesity with type 2 diabetes and insulin resistance in rodent models but its relevance to human diabetes remains uncertain. The aim of this study was to investigate the relationship between serum resistin concentrations with insulin resistance and obesity indices in type 2 diabetes and non-diabetic obese subjects.Met...

متن کامل

سطوح سرمی آدیپونکتین در افراد چاق دیابتی و غیردیابتی

Background: Adiponectin is an adipose tissue-derived hormone that low levels of this hormone are associated with obesity, insulin resistance, and type 2 diabetes. The aim of this study was to compare the serum levels of adiponectin in diabetic and non-diabetic obese individuals. Methods: As a cross-sectional study 35 obese individuals with type 2 diabetes mellitus and 35 non-diabetic obese subj...

متن کامل

The Effect of Eight Weeks of High-Intensity Interval Training and Endurance On Blood Glucose and TORC1 Protein Content in Subcutaneous Adipose Tissue of Obese with Type 2 Diabetes Rats

Background: TORC1 protein is an important factor in regulating adipose tissue metabolism. Type 2 diabetes can lead to dysfunction and the development of obesity. Therefore, the aim of the present study was to investigate the effect of eight weeks of high-intensity interval training (HIIT) and endurance on blood glucose and TORC1 protein content in subcutaneous adipose tissue of obese with type ...

متن کامل

شیوع اختلال تحمل گلـوکـز و دیابت نوع 2 در خانم های مبتلا به سندرم تخمدان پلی‌کیستیک و لزوم غربالگری کلیه خانم های با PCOS برای اختلال تحمل گلوکز

Background: Polycystic ovary syndrome (PCOS) which is characterized by menstrual irregularities (due to chronic anovulation) and hyperandrogenism is one of the most common endocrine disorders of women at reproductive age. The precise cause of PCOS is unknown, but it seems that several factors may have role in its pathogenesis. Insulin resistance and impaired insulin secretion are common finding...

متن کامل

بررسی تأثیر سیر روی لیپیدهای سرم و قند خون در بیماران دیابتی نوع II

Introduction: Hyperlipidemia and diabetes are common risk factors for ischemic heart disease, which is the main cause of mortality in diabetic patients. Strict control of blood glucose and other risk factors in diabetics has led to prevention of complications. Garlic has received particular attention for control of blood glucose and decrease in blood lipid levels. At present, several studies ha...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

عنوان ژورنال:
  • Prague medical report

دوره 106 3  شماره 

صفحات  -

تاریخ انتشار 2005